BAR-ILAN INSTITUTE OF NANOTECHNOLOGY & ADVANCED MATERIALS | 2019 ANNUAL REPORT

65 Dots Functionalized with Hydroxyapatite Nanoparticles”, ACS applied materials & interfaces, 2018 . • L Shani, VB Kumar, A Gedanken, I Shapiro, BY Shapiro, A Shaulov, Y Yeshurun, “Type-I superconductivity in carbon- coated Sn nano-spheres”, Physica C: Superconductivity and its Applications 546, 6-10, 2018 . • L Shani, VB Kumar, A Gedanken, I Shapiro, BY Shapiro, A Shaulov, Y Yeshurun, “Effect of carbon coating on the superconducting properties of Pb and Sn nano-spheres”, Journal of Physics: Conference Series 969 (1), 012045, 2018 . • VB Kumar, M Marcus, Z Porat, L Shani, Y Yeshurun, I Felner, O Shefi, Aharon Gedanken, “Ultrafine Highly Magnetic Fluorescent ќ -Fe2O3/ NCD Nanocomposites for Neuronal Manipulations”, ACS Omega 3 (2), 1897- 1903, 2018 . • HK Sadhanala, S Senapati, KV Harika, KK Nanda, A Gedanken, “Green synthesis of MoS2 nanoflowers for efficient degradation of methylene blue and crystal violet dyes under natural sun light conditions”, New Journal of Chemistry 42 (17), 14318-14324, 2018 . • VB Kumar, Z Porat, A Gedanken, “Improved photovoltaic properties of a back-contact electrode produced by copper deposition on carbon-dots/carbon paper”, Journal of Machine Construction and Maintenance. Problemy Eksploatacji, 2018 . • A Buslovich, B Horev, Y Shebis, V Rodov, A Gedanken, E Poverenov, “A facile method for the deposition of volatile natural compound-based nanoparticles on biodegradable polymer surfaces”, Journal of Materials Chemistry B 6 (15), 2240- 2249, 2018 . • M Moorthy, VB Kumar, Z Porat, A Gedanken, “Novel polymerization of aniline and pyrrole by carbon dots”, New Journal of Chemistry 42 (1), 535-540, 2018 . • I Perelshtein, N Perkas, A Gedanken, “The sonochemical functionalization of textiles”, The Impact and Prospects of Green Chemistry for Textile Technology, 161-198, 2018 . Book The sonochemical functionalization of textiles I Perelshtein, N Perkas, A Gedanken The Impact and Prospects of Green Chemistry for Textile Technology, 161-198, 2019 . Prof. Doron Gerber The Mina & Everard Goodman Faculty of Life Sciences Member of BINA, Nano-Medicine Center Research Areas • Virus host interactions • System biology • Microfluidics Abstract Integrated microfluidic applications for studying protein-protein interactions, gene regulation, intracellular mechanisms and whole cell intercellular studies. Rapidly increasing fields, such as systems biology, require the development and implementation of new technologies, enabling high-throughput and high- fidelity measurements of large systems. Microfluidics promises to fulfill many of these requirements, such as performing high-throughput screening experiments on-chip, encompassing biochemical, biophysical, and cell-based assays. We design, develop and apply integrated microfluidic devices for the investigation of protein-protein interactions, gene regulation, post translational modification and for screening of cells responses to drug libraries. These devices embed thousands of micromechanical valves on a single device with a postage-sized footprint. The application of microfluidics in these research fields reduces reaction times, increases sensitivity, decreases reagent consumption and enables high- throughput research. The potential impact of microfluidics on biological sciences is significant. A number of microfluidic- based assays have already provided novel insights into the structure and function of biological systems, and the field of microfluidics will continue to impact biology. Microfluidics device + assay for on chip autophosphorylation of an array of human proteins. Publications 2018 and 2019 • Ernst, Y Glucksam-Galnoy, B Bhatta, M Athamna, I Ben Dror, Y Glick, D Gerber, T Zor, “Exclusive temporal stimulation of IL-10 expression in LPS-Stimulated Mouse Macrophages by cAMP Inducers and Type I Interferons”, Frontiers in immunology 10, 1788, 2019 . • H Nevenzal, M Noach-Hirsh, O Skornik- Bustan, L Brio, E Barbiro-Michaely, Y Glick, D Avrahami, R Lahmi, A Tzur, D Gerber, “A high-throughput integrated microfluidics method enables tyrosine autophosphorylation discovery”, Communications biology 2 (1), 42, 2019 . • M Hen, E Edri, O Guy, D Avrahami, H Shpaisman, D Gerber, CN Sukenik, “Microfluidic Devices Containing ZnO Nanorods with Tunable Surface Chemistry and Wetting-Independent Water Mobility”, Langmuir 35 (9), 3265-3271, 2019 . • KS Rajan, T Doniger, S Cohen-Chalamish, D Chen, O Semo, S Aryal, E Glick Saar, V Chikne, D Gerber, R Unger, C Tschudi, S Michael, “Pseudouridines on Trypanosoma brucei spliceosomal small nuclear RNAs