BAR-ILAN INSTITUTE OF NANOTECHNOLOGY & ADVANCED MATERIALS | 2019 ANNUAL REPORT

81 Dr. Ilana Perelshtein HRTEM Member of BINA staff Publications 2018 and 2019 • Harika VK, Sadhanala HK, Perelshtein I, Gedanken A., “Sonication-Assisted Synthesis of Bimetallic Hg/Pd Alloy Nanoparticles for Catalytic Reduction of Nitrophenol and its Derivatives”. Ultrasonics Sonochemistry, 60, 104804, 2019 . • Huanli Xu, Ru Yuan, Xiaohui Liu, Xiao Li, Cong Li, Gan Qiao, I. Perelshtein, Aharon Gedanken, Xiukun Lin, “Novel Zn-doped CuO nanocomposites inhibit tumor growth in vitro and in vivo: involvement of reactive oxygen species-dependent apoptosis and autophagy cross-linked by NF-kappaB pathway“, Nanomedicine, 14(2),131-149, 2019 . • Nagvenkar, Anjani; Perelshtein, Ilana; Piunno, Ylenia; Mantecca, Paride; Gedanken, Aharon, “Sonochemical One- step Synthesis of Polymer-Capped Metal Oxide Nanocolloids: Antibacterial Activity and Cytotoxicity”, ACS Omega 4, 9, 13631- 13639, 2019 . • Ortal Lidor-Shalev, Reut Yemini, Nicole Leifer, Raju Nanda, Aviv Tibi, Ilana Perelshtein, Efrat Shawat Avraham, Yitzhak Mastai, and Malachi Noked, “Growth of Hybrid Inorganic/Organic Chiral Thin Films by Sequenced Vapor Deposition” ACS Nano, 13, 9, 10397-10404, 2019 . • Nina Armon, Ehud Greenberg, Eitan Edri, Avraham Kenigsberg, Silvia Piperno, Omree Kapon, Ohad Fleker, Ilana Perelshtein, Gili CohenTaguri, Idan Hod and Hagay Shpaisman, “Simultaneous laser-induced synthesis and micro-patterning of a metal organic framework”, Chem.Comm., 55, 12773-12776, 2019 . • Ayan Mukherjee, Tali Sharabani, Ilana Perelshtein and Malachi Noked, “Three Na+ ionactivity of hollow spherical Na 3 V 2 (PO 4 )2F 3 cathode: new aspects on Prof. Rachela Popovtzer Faculty of Engineering Member of BINA, Nano-Medicine Center Research Areas • Molecular CT imaging of cancer using targeted gold nanoparticles. • Theranostic approaches for Alzheimer’s and Parkinson’s Diseases. • Metabolic based imaging and therapy. • Optical/chamical imaging of enzymatic activity. • Nanoparticle-based strategies for targeted drug delivery. • In-vivo cell tracking techniques. Abstract Nanotheranostics for Personalized Medicine We strive to develop innovative nanotechnology-based solutions for broad applications, including early diagnosis of disease, targeted drug delivery with fewer side effects, and novel therapeutic approaches. Our vision is to have a major impact on the future of medicine. Our multidisciplinary research approach integrates researchers from engineering, chemistry, biology and medicine. high capacity and stability” Batteries & Supercaps, 2, 1–5 2019 . • M. Salat, P.Petkova, J. Hoyoa, I. Perelshtein, A. Gedanken, T. Tzanov, “Durable antimicrobial cotton textiles coated sonochemically with ZnO nanoparticles embedded in an in-situ enzymatically generated bioadhesive“ Carbohydrate Polymers, 189, 198–203, 2018 . • Nagvenkar, Anjani; Shani, Lior; Felner, Israel; I. Perelshtein; Gedanken, Aharon; Yeshurun, Yosef, “Surfactant Effect on the Thermal and Electrical Behaviors of Sonochemically Synthesized Fe and Fe-PVP Nanofluids and Insight into the Magnetism of Their in Situ Oxidized Ѓ -Fe Analogues”, The Journal of Physical Chemistry C, 122, 20755-20762, 2018 . Atomic/Molecular Layer Deposition (A/ MLD) Can molecular profiling enhance radiotherapy? Impact of personalized targeted gold nanoparticles on radiosensitivity and imaging of adenoid cystic carcinoma Publications 2018 and 2019 • Betzer, E Barnoy, T Sadan, I Elbaz, C Braverman, Z Liu, R Popovtzer, “Advances in imaging strategies for in vivo tracking of exosomes”, Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology;e1594, 2019 . • E Haimov-Talmoud, Y Harel, H Schori, M Motiei, A Atkins, R Popovtzer, JP Lellouche, O Shefi, “Magnetic Targeting of mTHPC to Improve the Selectivity and Efficiency of Photodynamic Therapy”, ACS applied materials & interfaces, 11, 49, 2019 . • M Rouchota, S Sarpaki, E Fragogeorgi, N Shraga-Heled, N Günday-Türeli, E Türeli, R Popovtzer, M Masa, G Loudos, “54: Structural and Functional Tracking of Stem Cells on a Muscle Regeneration Model Through Noninvasive Multimodal Imaging”, Transplantation 103 (9S2), S16-S17, 2019 . • S Guo, N Perets, O Betzer, S Ben-Shaul, A Sheinin, I Michaelevski, R Popovtzer, D Offen, S Levenberg, “Intranasal delivery of mesenchymal stem cell derived exosomes loaded with phosphatase and tensin homolog siRNA repairs complete spinal cord injury”, ACS nano 13 (9), 10015- 10028, 2019 . • EA Barnoy, M Motiei, C Tzror, S Rahimipour, R Popovtzer, D Fixler, “Biological Logic Gate Using Gold Nanoparticles and Fluorescence Lifetime Imaging Microscopy”, ACS Applied Nano Materials 2 (10), 6527-6536, 2019 . • L Feng, O Betzer, D Tao, T Sadan, R Popovtzer, Z Liu, “Oxygen Nanoshuttles for Tumor Oxygenation and Enhanced Cancer Treatment”, CCS Chemistry 1 (3), 239-250, 2019 . • Y Chemla, O Betzer, A Markus, N Farah, M Motiei, R Popovtzer, Y Mandel, “Gold nanoparticles for multimodal high-