BAR-ILAN INSTITUTE OF NANOTECHNOLOGY & ADVANCED MATERIALS | 2019 ANNUAL REPORT

82 resolution imaging of transplanted cells for retinal replacement therapy”, Nanomedicine 14 (14), 1857-1871, 2019 . • F Gong, L Cheng, N Yang, O Betzer, L Feng, Q Zhou, Y Li, R Chen, R Popovtzer, Z Liu, “Ultrasmall Oxygen ѧ Deficient Bimetallic Oxide MnWOX Nanoparticles for Depletion of Endogenous GSH and Enhanced Sonodynamic Cancer Therapy”, Advanced Materials, 31, 1900730, 2019 . • D Offen, N Perets, O Betzer, R Popovtzer, R Shapira, U Ashery, “Targeting damages in the brain: Exosomes derived from MSC present migration and homing abilities to different neurodegenerative and neuropsychiatric locations”, Cytotherapy 21 (5), e6, 2019 . • D Offen, N Perets, S Guo, O Betzer, R Popovtzer, S Ben-Shaul, A Sheinin, I Michaelevski, S Levenberg, “Exosomes loaded with PTEN siRNA leads to functional recovery after complete transection of the spinal cord by specifically targeting the damaged area”, Cytotherapy 21 (5), e7-e8, 2019 . • M Motiei, T Dreifuss, T Sadan, N Omer, T Blumenfeld-Katzir, E Fragogeorgi, G Loudos, R Popovtzer, N Ben-Eliezer, “Trimodal Nanoparticle Contrast Agent for CT, MRI and SPECT Imaging: Synthesis and Characterization of Radiolabeled Core/ Shell Iron Oxide@ Gold Nanoparticles”, Chemistry Letters 48 (3), 291-294, 2019 . • N Perets, O Betzer, R Shapira, S Brenstein, A Angel, T Sadan, U Ashery, R Popovtzer, D Offen, “Golden Exosomes Selectively Target Brain Pathologies in Neurodegenerative and Neurodevelopmental Disorders”, Nano letters, 19, 6, 3422-3431, 2019 . • E. A. Barnoy, R. Popovtzer, and D. Fixler, “Development of a molecular bioswitch using fluorescence lifetime imaging: Incremental activation of fluorescein diacetate,” J. Biophotonics, vol. 11, no. 2, 2018 . • T. Sadan, D. P. Cormode, and R. Popovtzer, “Nanoinformatics Revolutionizes Personalized Cancer Therapy,” Trends in Cancer, 2018 . • R. Meir and R. Popovtzer, “Cell tracking using gold nanoparticles and computed tomography imaging,” Wiley Interdiscip. Rev. Nanomedicine Nanobiotechnology, vol. 10, no. 2, 2018 . • E. S. Davidi et al., “Cisplatin-conjugated gold nanoparticles as a theranostic agent for head and neck cancer,” Head Neck, vol. 40, no. 1, pp. 70–78, Jan. 2018 . • Bier et al., “Placenta-derived mesenchymal stromal cells and their exosomes exert therapeutic effects in Duchenne muscular dystrophy,” Biomaterials, 174, 67-78, 2018 . • Y. Zhou et al., “Radiotherapy-Sensitized Tumor Photothermal Ablation Using Ѕ -Polyglutamic Acid Nanogels Loaded with Polypyrrole,” Biomacromolecules, p. acs. biomac.8b00184, Apr. 2018 . • H. K. Gaikwad, D. Tsvirkun, Y. Ben-Nun, E. Merquiol, R. Popovtzer, and G. Blum, “Molecular Imaging of Cancer Using X-ray Computed Tomography with Protease Targeted Iodinated Activity-Based Probes,” Nano Lett., vol. 18, no. 3, pp. 1582–1591, Mar. 2018 . • M Motiei, T Sadan, N Zilony, G Topaz, R Popovtzer, M Topaz”, Gold nanoparticles for tracking bacteria clearance by regulated irrigation and negative pressure- assisted wound therapy”, Nanomedicine 13 (15), 1835-1945, 2018 . • D Tsvirkun, Y Ben-Nun, E Merquiol, I Zlotver, K Meir, T Weiss-Sadan, Ilan Matok, Rachela Popovtzer, Galia Blum, “CT Imaging of Enzymatic Activity in Cancer Using Covalent Probes Reveal a Size-Dependent Pattern”, Journal of the American Chemical Society 140 (38), 12010-12020, 2018 . • T Dreifuss, TS Ben-Gal, K Shamalov, A Weiss, A Jacob, T Sadan, M Motiei, Rachela Popovtzer, “Uptake mechanism of metabolic-targeted gold nanoparticles”, Nanomedicine 13 (13), 1535-1549, 2018 . Prof. Yitzhak Rabin Department of Physics Member of BINA Research Areas • Biophysics • Soft condensed matter (polymers, gels, liquid crystals) and disordered solids • Interfaces and confined systems • Geometrical methods in physics Abstract Soft and Biological Matter Theoretical studies of APD (All Particles are Different) fluids and solids; Microbiome- host adaptation; Bacterial division; Reactions and phase separation in active systems; Scale-dependent viscoelasticity; NPC (nuclear pore complex) morphology. Snapshots of a system of 5000 particles at three different times. At t =0, particles are randomly distributed inside a circular region. Particles align themselves to form lines in the system ( t =700) and density of particles on the line increases as time progresses ( t =1400). Spatial segregation of distinct FG domains at the nanoscale