92 Prof. Mastai Yitzhak Department of Chemistry Member of BINA Nano-Materials Center Research Areas • Chirality • Chiral self-assembled monolayers • Liquids and water in nanoporous materials • Biomimetic chemistry • Nanomaterials Abstract Charity at the nanoscale Prof. Yitzhak Mastai His current research is focused on Nanoscale Chirality, Synthesis and Analysis of Chiral Nanosurfaces and Chiral self-assembled Monolayers and Polymeric Chiral Nanoparticles. Mastai and his colleagues, have gained international reputation in these fields, and have pioneered several new concepts and techniques in the following areas: SAM’s for the preparation of Chiral Nanosurfaces for Chiral resolution by crystallization. Chiral ordered Mesoporous silica by Chiral polymer -Templated Synthesis. An innovative new Carbon Chiral Mesoporous, based on the Carbonization of Chiral Ionic liquids. The development of Optical Scanning Microscopy (NSOM) and Isothermal Titration Calorimetry (ITC) for the determination of Nanoscale Chirality. HE-TEM images of Chiral Titania (TiO2) nanofilms. Publications 2020 and 2021 • Gil Otis, Michal Ejgenberg, Yitzhak Mastai. “Solvent-Free Mechanochemical Synthesis of ZnO Nanoparticles by HighEnergy Ball Milling of ε-Zn(OH)2 Crystals”. Nanomaterials, 2021. • Akmaral B Rakhym, Gulziya A Seilkhanova, Yitzhak Mastai. “Physicochemical evaluation of the effect of natural zeolite modification with didodecyldimethylammonium bromide on the adsorption of Bisphenol-A and Propranolol Hydrochloride”. Microporous and Mesoporous Materials, 2021. • Milena Perovic, Sapir Shekef Aloni, Wuyong Zhang, Yitzhak Mastai, Markus Antonietti, Martin Oschatz. “Toward Efficient Synthesis of Porous All-Carbon-Based Nanocomposites for Enantiospecific Separation”. ACS Applied Materials & Interfaces, 2021. • Zarina Baranchiyeva, Gulziya Seilkhanova, Akmaral Rakhym, Yitzhak Mastai, Yenlik Ussipbekova. “Adsorption of Pb (II) and Cd (II) from aqueous solutions on polyvinylpyrrolidone modified Kyzylsok natural clay”. International Journal of Biology and Chemistry, 2021. • Kusha Sharma, Hari Krishna Sadhanala, Yitzhak Mastai, Ze’ev Porat, Aharon Gedanken. “Sonochemically Prepared BSA Microspheres as Adsorbents for the Removal of Organic Pollutants from Water”. Langmuir, 2021. • Maria Nihamkin, Avinoam Isaak, Amnon Albeck, Yitzhak Mastai, Yoni Toker. “Gas Phase Bond Formation in Dipeptide Clusters”. The Journal of Physical Chemistry Letters, 2020. • Meir Abuaf, Yitzhak Mastai. “Synthesis of Multi Amino Acid Chiral Polymeric Microparticles for Enantioselective Chemistry”. Macromolecular Chemistry and Physics, 2020. • Milena Perovic, Sapir Shekef Aloni, Yitzhak Mastai, Martin Oschatz. “Mesoporous carbon materials with enantioselective surface obtained by nanocasting for selective adsorption of chiral molecules from solution and the gas phase”. Carbon, 2020. • Yamala, A. K.; Nadella, V.; Mastai, Y.; Prakash, H.; Paik, P., “P-LME polymer nanocapsules stimulate naive macrophages and protect them from oxidative damage during controlled drug release.” Journal of Applied Polymer Science, 2020, 137 (6). • Kenessova, A. K.; Seilkhanova, G. A.; Rakhym, A. B.; Mastai, Y. “Composite materials based on orange and pomegranate peels for Cu (II) and Zn (II) ions extraction.” International Journal of Biology and Chemistry, 2020, 13 (1), 154160. • Otis, G.; Nassir, M.; Zutta, M.; Saady, A.; Ruthstein, S.; Mastai, Y. “Enantioselective crystallization of chiral inorganic crystals of epsilon-Zn(OH)2 with amino acids”. Angewandte Chemie (International ed. in English), 2020. Prof. Michaeli Shulamit Vice President for Research The Mina & Everard Goodman Faculty of Life Sciences Member of BINA Nano-Medicine Center Research Areas • Mechanism and machinery of nucleolar gene silencing • The use of nanoparticles for cytoplasmic and nuclear gene silencing • Trans-splicing in trypanosomatids • Protein translocation in trypanosomatids • RNA modifications mediated by guide RNAs • RNAi silencing in plants • The use of nano particles as RNAi carriers into the nucleous Publications 2020 and 2021 • Oded Cohen, Oshra Betzer, Noy Elmaliach-Pnini, Menachem Motiei, Tamar Sadan, Moran Cohen-Berkman, Or Dagan, Aron Popovtzer, Ady Yosepovich, Hana Barhom, Shulamit Michaeli, Rachela Popovtzer. “‘Golden’exosomes as delivery vehicles to target tumors and overcome intratumoral barriers: in vivo tracking in a model for head and neck cancer”. Biomaterials science, 2021. • Sriram Kannan, Yifat Harel, Liron Limor Israel, Emmanuel Lellouche, Alexander Varvak, Merav Nadav Tsubery, Jean-Paul Lellouche, Shulamit Michaeli. “Novel Nanocarrier Platform for Effective Treatment of Visceral Leishmaniasis”. Bioconjugate Chemistry, 2021. • K Shanmugha Rajan, Katerina Adler, Hava Madmoni, Dana Peleg-Chen, Smadar Cohen-Chalamish, Tirza Doniger, Beathrice Galili, Doron Gerber, Ron Unger, Christian Tschudi, Shulamit Michaeli. “Pseudouridines on Trypanosoma brucei mRNAs are developmentally regulated: Implications to mRNA stability and protein binding”. Molecular Microbiology, 2021. • Neta Regev-Rudzki, Shulamit Michaeli, Ana Claudia Torrecilhas. “Extracellular Vesicles in Infectious Diseases Frontiers in Cellular and Infection Microbiology”.
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