2022 ANNUAL REPORT

Ripples of Impact Eli Varon, a PhD student at Prof. Orit Shefi’s Lab, is developing a novel technology that will significantly improve the effectiveness and safety of personalized cancer treatments. The method is based on the use of light-sensitive nanoparticles and a personal predictive machine-learning model. The method can be applied as a local cancer treatment that relies on the administration of a photosensitizer or photothermal agent, which can absorb electromagnetic radiation and convert it into heat or a destructive chemical reaction. Dr. Amos Danielli and his PhD student, Shira Ruth, developed a magnetic modulation-based system that can detect protein-protein connections and, for the first time, proteinDNA interactions as well, with great precision. Being simple to operate and cost-effective, the system that provides results in only two hours can enhance biomedical research and lead to new drug development for cancer, diabetes and many other severe diseases. Dr. Eran Avraham and Dr. Izaak Cohen from Prof. Doron Aurbach’s lab developed a machine that uses tap water to produce safe and environmentallyfriendly disinfectants that can eliminate bacteria and viruses from surfaces, crops and the body. With over 99.999% efficiency, the system is easy to use and adjustable for different purposes. What started out as an idea driven by the COVID-19 outbreak became a working machine to be sold under the Purific Solutions LTD brand. The effectiveness of the technology to reduce the contamination level in real conditions in hospitals is destined to be evaluated at Baruch Padeh (Poriya) Medical Center (a planned pilot). 33

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