2022 ANNUAL REPORT

52 TEM micrographs of S. aureus (cyan) treated with the synthesized nanoparticles (yellow). The nano particles target bacteria and mark them for destruction. Publications 2021 and 2022 • Akanksha Gupta, Moorthy Maruthapandi, Poushali Das, Arumugam Saravanan, Gila Jacobi, Michal Natan, Ehud Banin, John HT Luong, Aharon Gedanken. “Cuprous Oxide Nanoparticles Decorated Fabric Materials with Anti-biofilm Properties”. ACS Applied Bio Materials, 2022. • Aleksandra Ivanova, Kristina Ivanova, Luisa Fiandra, Paride Mantecca, Tiziano Catelani, Michal Natan, Ehud Banin, Gila Jacobi, Tzanko Tzanov. “Antibacterial, Antibiofilm, and Antiviral FarnesolContaining Nanoparticles Prevent Staphylococcus aureus from Drug Resistance Development”. International Journal of Molecular Sciences, 2022. • Angela Gala Morena, Arnau Bassegoda, Michal Natan, Gila Jacobi, Ehud Banin, Tzanko Tzanov. “Antibacterial Properties and Mechanisms of Action of Sonoenzymatically Synthesized LigninBased Nanoparticles”. ACS Applied Materials & Interfaces, 2022. • Esther Shmidov, Ilana Lebenthal-Loinger, Shira Roth, Sarit Karako-Lampert, Itzhak Zander, Sivan Shoshani, Amos Danielli, Ehud Banin. “PrrT/A, a Pseudomonas aeruginosa Bacterial Encoded ToxinAntitoxin System Involved in Prophage Regulation and Biofilm Formation”. Microbiology Spectrum, 2022. • Yevgenia Shebis, Alexander Laskavy, Anat Molad-Filossof, Hadar Arnon-Rips, Michal Natan-Warhaftig, Gila Jacobi, Elazar Fallik, Ehud Banin, Elena Poverenov. “NonCycling through Solid-State Nuclear Magnetic Resonance Analysis”. Advanced Energy and Sustainability Research, 2021. · Yujia Lv, Dawei Liang, Shanfu Lu, Doron Aurbach, Yan Xiang. “Unidirectional electron injection and accelerated proton transport in bacteriorhodopsin based Bio-pn junctions”. Biosensors and Bioelectronics, 2021. · Sandipan Maiti, Hadar Sclar, Rosy Sharma, Noam Vishkin, Miryam FayenaGreenstein, Judith Grinblat, Michael Talianker, Larisa Burstein, Nickolay Solomatin, Ortal Tiurin, Yair Ein-Eli, Malachi Noked, Boris Markovsky, Doron Aurbach. “Understanding the Role of Alumina (Al2O3), Pentalithium Aluminate (Li5AlO4), and Pentasodium Aluminate (Na5AlO4) Coatings on the Li and MnRich NCM Cathode Material 0.33Li2Mn O3·0.67Li(Ni0.4Co0.2Mn0.4)O2 for Enhanced Electrochemical Performance”. Advanced Functional Materials, 2021. · Elena Levi, Doron Aurbach, Carlo Gatti. “Metal–Metal Bond in the Light of Pauling’s Rules”. Molecules, 2021. · Elena Levi, Doron Aurbach, Carlo Gatti. “Redox Potential and Crystal Chemistry of Hexanuclear Cluster Compounds”. Molecules, 2021. · Fyodor Malchik, Netanel Shpigel, Mikhael D Levi, Tirupathi Rao Penki, Bar Gavriel, Gil Bergman, Meital Turgeman, Doron Aurbach, Yury Gogotsi. “MXene conductive binder for improving performance of sodium-ion anodes in water-in-salt electrolyte”. Nano Energy, 2021. · Francis Amalraj Susai, Daniela Kovacheva, Tatyana Kravchuk, Yaron Kauffmann, Sandipan Maiti, Arup Chakraborty, Sooraj Kunnikuruvan, Michael Talianker, Hadar Sclar, Yafit Fleger, Boris Markovsky, Doron Aurbach. “Studies of Nickel-Rich LiNi0.85Co0.10Mn0.05O2 Cathode Materials Doped with Molybdenum Ions for Lithium-Ion Batteries”. Materials, 2021. · Meital Turgeman, Miryam FayenaGreenstein, Shaul Bublil, Netanel Shpigel, Merav Nadav Tsubery, Munseok Chae, Yuval Elias, Doron Aurbach. “Improved High-Energy Na-NCM Cathode Prepared by Ion Exchange Route via Application of Various ALD Treatments”. Journal of The Electrochemical Society, 2021. · S Maddukuri, A Nimkar, MS Chae, TR Penki, S Luski, D Aurbach. “Na0.44MnO2/ Polyimide Aqueous Na-ion Batteries for Large Energy Storage Applications”. Energy Res, 2021. · Elena Levi, Doron Aurbach, Carlo Gatti. “Redox Potential and Crystal Chemistry of Hexanuclear Cluster Compounds”. Molecules, 2021. · Barak Shapira, Tirupathi Rao Penki, Izaak Cohen, Yuval Elias, Raphael Dalpke, André Beyer, Armin Gölzhäuser, Eran Avraham, Doron Aurbach. “Combined nanofiltration and advanced oxidation processes with bifunctional carbon nanomembranes”. RSC Advances, 2021. · Villa Krishna Harika, Tirupathi Rao Penki, Boddapati Loukya, Atanu Samanta, GuiLiang Xu, Cheng-Jun Sun, Ilya Grinberg, Francis Leonard Deepak, Khalil Amine, Doron Aurbach, Aharon Gedanken. “Sustainable existence of solid mercury (Hg) nanoparticles at room temperature and their applications”. Chemical Science, 2021. Prof. Banin Ehud The Mina & Everard Goodman Faculty of Life Sciences Member of BINA Medicine Center Cleantech Center Research Areas • Bacterial biofilms • Nanoparticles with anti-biofilm properties • Bacterial virulence • Bio-ethanol production Abstract The Biofilm Research Laboratory Our lab focuses on microbial biofilms, with the aim of understanding the signals and processes that promote biofilm formation and finding new methods for treating biofilm-related medical, industrial and environmental problems. Nanotechnology can provide new opportunities for preventing and fighting biofilm-mediated problems via atomic-scale tailored nanomaterials. Our group is exploring the utility of potential antimicrobial / antibiofilm nanomaterials including metal fluorides, metal oxides and N-halamine nanoparticles which can provide long lasting rechargeable antibiofilm/ antimicrobial activity.

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