58 Prof. Danielli Amos Faculty of Engineering Member of BINA Medicine Center Magnetism Center Research Areas • Rapid and highly sensitive detection of biomarkers, such as proteins and specific DNA sequences • Detection of protein-protein interactions • Magnetic manipulation of nanoparticles, design of magnetic poles, magnetic force optimization Abstract Optical Imaging and Biosensing We develop high-sensitivity, point-of-care (POC) methods to detect and measure low concentrations of biomarkers. Clinical adoption of our devices could spur development for other medical applications that could benefit from point-of-care, high sensitivity biomarker detection, including detection of head injuries biomarkers, viruses, etc. Magnetic modulation biosensing (MMB) system combines magnetic and fluorescent labeling to measure ultra-low biomarker concentrations, allowing rapid and sensitive detection. Publications 2021 and 2022 · Esther Shmidov, Ilana Lebenthal-Loinger, Shira Roth, Sarit Karako-Lampert, Itzhak Zander, Sivan Shoshani, Amos Danielli, Ehud Banin. “PrrT/A, a Pseudomonas aeruginosa Bacterial Encoded ToxinAntitoxin System Involved in Prophage Regulation and Biofilm Formation”. Microbiology Spectrum, 2022. · Shira Roth, Michael Margulis, Amos Danielli. “Recent Advances in Rapid and Highly Sensitive Detection of Proteins and Specific DNA Sequences Using a Magnetic Modulation Biosensing System”. Sensors 22 (12), 4497, 2022. · Shmuel Burg, Shira Roth, Meir Cohen, Shira Avivi-Mintz, Michael Margulis, Hanan Rohana, Avi Peretz, Amos Danielli. “High throughput optical modulation biosensing for highly sensitive and rapid detection of biomarkers”. Talanta, 2022. · Shira Avivi-Mintz, Yaniv Lustig, Victoria Indenbaum, Eli Schwartz, Amos Danielli. “Highly Sensitive and Specific SARS-CoV-2 Serological Assay Using a Magnetic Modulation Biosensing System”. Biosensors, 2021. · Michael Margulis, Meir Cohen, Shmuel Burg, Shira Avivi-Mintz, Amos Danielli. “Optical modulation biosensing system for rapid detection of biological targets at low concentrations”. Biomedical Optics Express, 2021. · Michael Margulis, Oran Erster, Shira Roth, Michal Mandelboim, Amos Danielli. “A Magnetic Modulation Biosensing-Based Molecular Assay for Rapid and Highly Sensitive Clinical Diagnosis of Coronavirus Disease 2019 (COVID-19)”. The Journal of Molecular Diagnostics, 2021. · Shira Roth, Amos Danielli. “Magnetic modulation biosensing: How it works and how it can be used to detect the Zika virus”. Zika Virus Impact, Diagnosis, Control, and Models, 231-241, 2021. · Shira Roth, Amos Danielli. “Rapid and Sensitive Inhibitor Screening Using Magnetically Modulated Biosensors”. Sensors, 2021. Dr. Desiatov Boris Faculty of Engineering Member of BINA Nano & Advanced Materials Center Photonics Center Quantum Center Research Areas Quantum electro-optic devices • Optoelectronic device • Quantum optics • Quantum information science • Meta-Materials • Nano Photonics • Nanofabrication • Non linear optics Abstract The world of quantum optics holds enormous potential to address a large variety of unsolved problems in sensing, information processing, computation, and precise measurements. Taking the advantage of well-developed nano fabrication processes, on-chip integrated quantum photonics is a promising platform for the realization of quantum optics technology. Artistic illustration of opto-electric on-chip quantum circuit. Publications 2021 and 2022 · Aharon Weiss, Christian Frydendahl, Jonathan Bar-David, Roy Zektzer, Eitan Edrei, Jacob Engelberg, Noa Mazurski, Boris Desiatov, Uriel Levy. “Tunable Metasurface Using Thin-Film Lithium Niobate in the Telecom Regime”. ACS Photonics, 2022.
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