66 phase reaction using twofurnace chemical vapor deposition system”. Chemical Papers, 2022. · O. Girshevitz, N. Cohen-Sinai, A. Zahavi, Y. Vardizer, D. Fixler. “Trace Elements in Tears: Comparison of Rural and Urban Populations Using Particle Induced X-ray Emission”. Journal of Personalized Medicine 12 (10), 1633, 2022. · N.M. Yitzhak, O. Girshevitz, A. Haran, A. Butenko, M. Kaveh, I. Shlimak. “Evidence of structural changes in ion-irradiated graphene independent of the incident ions mass”. Applied Surface Science, 153701, 2022. · Omer Kaspi, Osnat Israelsohn-Azulay, Yigal Zidon, Hila Rosengarten, Matea Krmpotić, Sabrina Gouasmia, Iva Bogdanović Radović, Pasi Jalkanen, Anna Liski, Kenichiro Mizohata, Jyrki Räisänen, Olga Girshevitz, Hanoch Senderowitz. “Inter-laboratory workflow for forensic applications: Classification of car glass fragments”. Forensic Science International, 333, 111216, 2022. · Mirit Hen, Leroy Dokhanian, Etai Grunwald, Matan Slook, Moshe Katzman, Maayan Priel, Olga Girshevitz, and Avi Zadok. “Thin layers analysis using surface acoustic wave-photonic devices in silicon-on-insulator”. Optics Express, 30(5), 6949-6959, 2022. · N.M. Yitzhak, O. Girshevitz, Y. Fleger, A. Haran, S. Katz, A. Butenko, M. Kaveh, I. Shlimak. “Analysis of fluctuations in the Raman spectra of suspended and supported graphene films”. Applied Surface Science, (536), 147812, 2021. · Madina Telkhozhayeva, Eti Teblum, Rajashree Konar, Olga Girshevitz, Ilana Perelshtein, Hagit Aviv, Yaakov R. Tischler, and Gilbert Daniel Nessim. “Higher Ultrasonic Frequency Liquid Phase Exfoliation Leads to Larger and Monolayer to Few-Layer Flakes of 2D Layered Materials”. Langmuir, 2021. · Lior Shani, Avital Fried, Yafit Flege, Olga Girshevitz, Amos Sharoni and Yosef Yeshurun. “Effect of Focused Ion Beam irradiation on superconducting nanowires”. Journal of superconductivity and novel magnetism, 2021. · Eitan Edri, Nina Armon, Ehud Greenberg, Shlomit Moshe-Tsurel, Danielle Lubotzky, Tommaso Salzillo, Ilana Perelshtein, Maria Tkachev, Olga Girshevitz, and Hagay Shpaisman. “Laser Printing of Multilayered Alternately Conducting and Insulating Microstructures”. Applied Materials & Interfaces, 2021. · Omer Kaspi, Olga Girshevitz, Hanoch Senderowitz. “PIXE based, MachineLearning (PIXEL) supported workflow for glass fragments classification”. Talanta, 2021. Dr. Golub Eyal Department of Chemistry Member of BINA Nano & Advanced Materials Center Bioconvergence Center Biomedicine Center Research Areas Protein-DNA interactions and proteinbased materials Abstract The Golub lab aims to elucidate the mechanisms that govern various aspects of nanobiotechnology and harness them to generate the next-generation of biomaterials. On the one hand, we focus on elucidating the various mechanisms that govern non-canonical DNA-protein interactions at important biological crossroads from a biophysical perspective. Derived insights could serve in the future as a solid foundation for the development of highly selective and specific ligands, both for therapeutic purposes as well as for the development of sensitive biosensors. Additionally, methods for the preparation of novel protein-based nanobiomaterials and nanoreactors are being devised based on revolutionary protein building blocks. Such materials aim to harness the structural diversity and precision that can be found in proteins with the nanosized effects that stem from nanostructures. Our work focuses on designing proteins for protein-based materials and to explore protein-DNA interactions. Publications 2021 and 2022 · Albert Kakkis, Eyal Golub, Tae Su Choi, F Akif Tezcan. “Redox- and metal-directed structural diversification in designed metalloprotein assemblies“. Chem. Commun., 58, 6958-6961, 2022. · Rohit H Subramanian, Jie Zhu, Jake B Bailey, Jerika A Chiong, Yiying Li, Eyal Golub, F Akif Tezcan. “Design of metal-mediated protein assemblies via hydroxamic acid functionalities”. Nature Protocols, volume 16, pages 3264–3297, 2021. Dr. Gonen Nitzan The Mina & Everard Goodman Faculty of Life Sciences Member of BINA Medicine Center Research Areas Sex Determination • 3D Genome organisation • CRISPR genome editing • Stem Cell Biology • Developing in vitro systems to model the gonads Abstract The Mammalian Sex Determination Lab Studying the role of the non-coding genome during sex determination A main research interest of our lab is to understand, at the molecular level, how sex is determined during embryonic development, i.e., how does an embryo develop into either male or female. In mammals, sex determination is genetically driven with XY individuals developing as males and XX individuals developing as females. However, if the process of sex determination is impaired, patients appear as XY females or XX males (sex reverse). These are all classified as patients with Disorders of Sex Development (DSD), with a prevalence of 1: 2500-4000 newborns. In the lab, we use the mouse as a model system and are interested at understanding the regulation of the key transcription factors controlling gonad formation and
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