84 Prof. Popovtzer Rachela Faculty of Engineering Member of BINA Medicine Center Research Areas · Molecular CT imaging of cancer using targeted gold nanoparticles. · Theranostic approaches for Alzheimer’s and Parkinson’s Diseases. · Metabolic based imaging and therapy. · Optical/chamical imaging of enzymatic activity. · Nanoparticle-based strategies for targeted drug delivery. · In-vivo cell tracking techniques. Abstract Nanotheranostics for Personalized Medicine We strive to develop innovative nanotechnology-based solutions for broad applications, including early diagnosis of disease, targeted drug delivery with reduced side effects, and novel therapeutic approaches. Our vision is to have a major impact on the future of medicine. Our multidisciplinary research approach integrates researchers from the fields of engineering, chemistry, biology and medicine, and consolidates advances in nanomaterials with imaging, specific biomarkers and therapeutics. Molecular CT imaging of cancer using targeted gold nanoparticles Publications 2021 and 2022 · H Pe’er-Nissan, H Ahdoot-Levi, O Betzer, PS Itzhak, N Shraga-Heled, I Gispan, M Motiei, A Doroshev, Y Anker, R Popovtzer. Dr. Perelshtein Ilana Head of CPM Unit & Synthesis of Smart Materials Unit Member of BINA staff Publications 2021 and 2022 · K. Dabbah, I. Perelshtein, A. Gedanken, Y. Houri-Haddad, O. Feuerstein. “Effects of ZnCuO nano-coated titanium surface on bacterial and host cells”. Materials, 2022, 15, 2514. · P. Das, S. Ganguly, I. Perelshtein, S. Margel, and A.Gedanken “Acoustic Green Synthesis of Graphene-Gallium Nanoparticles and PEDOT:PSS Hybrid Coating for Textile To Mitigate Electromagnetic Radiation Pollution”. ACS Appl. Mater&Interf. 2022 5, 1, 1644– 1655. · P. Shriber, M. Tkachev, A. Atkins, I. Perelshtein, S. Bretler, B. Schmerling, Y. Fleger*, G. Mariotto, M. Giarola, G. Daniel Nessim. “Synthesis of Nickel Sulfide Dendrites from Nickel Foil Using Thermal Annealing”. Materialia 2022, 21, 101316. · N. Dudchenko, S. Pawar, I. Perelshtein, D. Fixler. “Magnetite nanoparticles: synthesis and applications in optics and nanophotonics”. Materials 2022, 15, 2601. · I. Perelshtein, I. Levi, N. Perkas, A. Pollak, A. Gedanken. “CuO-coated Antibacterial and Antiviral Car Air-Conditioning Filters”. ACS. Appl. Mater.&Interf. 2022, 14, 21, 24850–24855 · B. Malik, S. Majumder, R.Lorenzi, I. Perelshtein, M. Ejgenberg, A. Paleari, G. Daniel Nessim “Promising Electrocatalytic Water and Methanol Oxidation Reaction Activity by Nickel Doped HematiteSurface Oxidized Carbon Nanotubes Composite Structures”. ChemPlusChem. 2022, 87, e2022000. · R. Bengalli, A. Colantuoni1, I. Perelshtein, A. Gedanken, M. Collini, P. Mantecca1and L. Fiandra. “In vitro skin toxicity of CuO and ZnO nanoparticles: application in the safety assessment of antimicrobial coated textiles”. NanoImpact, 2021, 21, 100282 · A. Moumen, R. Konar, D. Zappa, E. Teblum, I. Perelshtein, R. Lavi, S. Ruthstein, G. Daniel Nessim, and E. Comini. “Robust Room-Temperature NO2 Sensors from Exfoliated 2D Few-Layered CVD-Grown Bulk Tungsten Di-selenide (2H-WSe2)”. ACS Appl. Mater. Interfaces 2021, 13(3), 4316–4329. · Eitan Edri, Nina Armon, Ehud Greenberg, Shlomit Moshe-Tsure, Danielle Lubotzky, Tommaso Salzillo, Ilana Perelshtein, Maria Tkachev, Olga Girshevitz and Hagay Shpaisman. “Laser printing of multi-layered alternately conducting and insulating micro-structures”. Appl. Mat.&Inter. 2021, 13, 30, 36416–36425. · Telkhozhayeva, Madina; Teblum, Eti; Konar, Rajashree; Girshevitz, Olga; Perelshtein, Ilana; Aviv, Hagit; Tischler, Yaakov R.; Nessim, Gilbert. “Higher Ultrasonic Frequency Liquid Phase Exfoliation Leads to Larger and Monolayer to Few-Layer Flakes of 2D Layered Materials”. Langmuir. 2021., 37, 15, 4504– 4514 · Slavin, Yael; Ivanova, Kristina; Hoyo, Javier; Perelshtein, Ilana; Owen, Gethin; Haegert, Anne; Lin, Yen-Yi; Le Bian, Stephane; Gedanken, A; Hafeli, Urs; Tzanov, Tzanko; Bach, Horacio. “Novel lignin-capped silver nanoparticles against multidrug-resistant bacteria”. ACS Applied Materials & Interfaces, 2021, 13, 19, 22098–22109. · T. Iline-Vul, S. Bretler, S. Cohen, I. Perelshtein, N. Perkas, A. Gedanken and S. Margel. “Engineering of Superhydrophobic Silica Microparticles and Thin Coatings on Polymeric Films by Ultrasound Irradiation”. Mater. Today Chem, 2021, 21, 100520. · Tali Sharabani, Sarah Taragin, Ilana Perelshtein, Malachi Noked, and Ayan Mukherjee. “Interfacial Engineering of Na3V2(PO4)2F3 Hollow Spheres through Atomic Layer Deposition of TiO2: Boosting Capacity and Mitigating Structural Instability”. Small, 2021, 2104416. · Aleksandra Ivanova, Kristina Ivanova, Ilana Perelshtein, Aharon Gedanken, Katerina Todorova, Rositsa Milcheva, Petar Dimitrov, Teodora Popova, Tzanko Tzanov. “Sonochemically engineered nano-enabled zinc oxide/amylase coatings prevent the occurrence of catheter-associated urinary tract infections”. Materials Science and Engineering: C. 131. 2021 112518.
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