2022 ANNUAL REPORT

Prof. Dror Fixler and his team joined Prof. JeanPaul Lellouche’s lab manager, Dr. Yifat Harel, along with PhD student Daniel Itzhak, to develop novel nanodiamond-particles small enough to permeate skin layers and safely carry drugs for medical or cosmetic purposes. Monitoring these nano-diamonds in the body is essential, and, as published in ACS Nano (16.10.2022), the researchers also developed a new optical technology, blue laser-beam-based technology that safely and noninvasively provides their location and accumulation enabling to ensure no off-target penetration to the bloodstream or sensitive organs. Prof. Popovtzer breaks through the bloodbrain barrier and shuttles her innovative gold nanoplatforms, coupled with CRISPR biomolecules, to cure rare genetic brain diseases. With the support of the ERC grant, her outstanding BrainCRISPR research will make a far-reaching impact on next-generation medicine and many patients’ health across the world. Ripples of Impact 9

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