95 · Henning Zettergren, Alicja Domaracka, Thomas Schlathölter, Paola Bolognesi, Sergio Díaz-Tendero, Marta Łabuda, Sanja Tosic, Sylvain Maclot, Per Johnsson, Amanda Steber, Denis Tikhonov, Mattea Carmen Castrovilli, Lorenzo Avaldi, S adia Bari, Aleksandar R Milosavljević, Alicia Palacios, Shirin Faraji, Dariusz G Piekarski, Patrick Rousseau, Daniela Ascenzi, Claire Romanzin, Ewa Erdmann, Manuel Alcamí,Janina Kopyra, Paulo Limão-Vieira, Jaroslav Koči ek, Juraj Fedor, Simon Albertini, Michael Gatchell, Henrik Cederquist, Henning T Schmidt, Elisabeth Gruber, Lars H Andersen, Oded Heber, Yoni Toker, Klavs Hansen, Jennifer A Noble, Christophe Jouvet, Christina Kjær, Steen Brøndsted Nielsen, Eduardo Carrascosa, James Bull, Alessandra Candian, Annemieke Petrignani. “Roadmap on dynamics of molecules and clusters in the gas phase”. The European Physical Journal D, 2021. Dr. Tzur Amit The Mina & Everard Goodman Faculty of Life Sciences Member of BINA Medicine Center Research Areas • The mammalian cell cycle • Cell growth and size homeostasis of proliferating cells Publications 2021 and 2022 · Danit Wasserman, Sapir Nachum, Meirav Noach-Hirsh, Naomi Auerbach, Evelin Sheinberger-Chorni, Taylor P Enrico, Roxane Lahmi, Michael J Emanuele, Amit Tzur. “Elucidating Human Mitosis Using an Anaphase-Like Cell-Free System.” Cell Cycle Oscillators, 143-164, 2021. · E Panet, SHO Shalom, O Kraus, I Shoval, R Lahmi, H Shapiro, A Tzur. “Use of cell doublets for studying cytokinesis regulation reveals a new form of cytokinesis regression”. Research Square, 27 Jul 2021. Prof. Weiss Shimon Department of Physics BIU Department of Chemistry and Biochemistry UCLA Member of BINA Medicine Center Photonic Center Research Areas • Single molecule detection and spectroscopy, • Dynamic structural/molecular biology, • Protein folding, protein-protein and protein-DNA interactions, • Novel Bio-Nano-Technology probes, semiconductor nanocrystals, quantum dots, semiconductor nanocrystals voltage sensors, • Fluorescence microscopy/spectroscopy, super resolution microscopy • Mesoscopic systems Abstract Voltage Sensing Nano Particle as an Optical Tool for Electrical Potential Activity in Neurons Voltage sensing nanoparticles (vsNPs) have been developed for non invasive optical recording of membrane potential at the single particle and nanoscale level, at multiple sites, in a large field-of-view. vsNPs allow for ‘pointy’, single particle voltage detection. However, they still face challenges and additional improvements are needed before this new generation of sensors can be widely translated to neurophysiological applications. We developing targetable membrane potential nanosensors (MPNs) that optically and non-invasively record MPs at multiple sites in a large field of-view (FoV) of primary cultured neurons with single-particle brightness and voltage sensing capacity at the nanoscale. We searching for the ultimate nanometer size particle suitable for site specific voltage membrane sensing on the nanoscale. We therefore studied and developing different systems. Single-particle membrane potential optical recordings from NDTF,Cy5-Ab-avidin complex targeting GABAAR and DPA in cultured cortical neurons. Publications 2021 and 2022 · Arkaprabha Basu, Manash K Paul, Mitchel Alioscha-Perez, Grosberg Anna, Hichem Sahli, Steven M Dubinett, Shimon Weiss. “Statistical Parametrization of Cell Cytoskeleton (SPOCC) reveals novel lung cancer cytoskeletal phenotype with partial EMT signature”. Communications Biology, 2022. · Jenjamin Ambrose, Victoria E Hill, Robert A Shaw, Tristan Johnston-Wood, Matthew Willmott, Callum Johnston, Rebecca Mächtel, Thorben Cordes, Eitan Lerner, JG Hill, Shimon Weiss, Timothy D Craggs. “A novel single molecule fluorescence quenching technique for measuring distances below 3 nm”. Biophysical Journal, 2022. · Debjit Roy, Xavier Michalet, Evan W Miller, Robert P Gunsalus, Robert T Clubb, Shimon Weiss. “Bacterial resting membrane potential: a case study with Bacillus subtilis”. Biophysical Journal, 2022. · Debjit Roy, Zehavit Shapira, Shimon Weiss. “Membrane potential sensing: Material design and method development for single particle optical electrophysiology”. The Journal of Chemical Physics, 2022. · Jason T Smith, Alena Rudkouskaya, Shan Gao,Arin Ulku, Claudio Bruschini, Edoardo Charbon, Shimon Weiss, Margarida MR Barroso, Xavier Intes, Xavier Michalet. “Characterization of a large gated SPAD array for widefield NIR fluorescence lifetime imaging in vitro and in vivo”. Biophysical Journal, 2022. · Jason T Smith, Alena Rudkouskaya, Shan Gao, Juhi M Gupta, Arin Ulku, Claudio Bruschini, Edoardo Charbon, Shimon Weiss, Margarida Barroso, Xavier Intes,
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