42 BINA Equipment Center A Hub for Research and Industrial Partnerships Synthesis of Smart Materials Unit Head of Unit: Dr. Ilana Perelshtein Research areas: • iron oxides nanoparticles synthesis, transformations, characterisation • synthesis, functionalization, vectorization, characterisation and application of nanoparticles • biomineralogy • biomagnetism, substance magnetic properties • biological and medical application of functionalized synthetic nanoparticles (diagnostics and therapy, targeted drug delivery, bioimaging, etc.) Projects and Achievements of Smart Materials Unit 2023-2022: • Highly fluorescent Carbon Dots, obtained via onepot hydrothermal green synthesis using Rosemary and Lavender leaves exhibited antibacterial activity against both Gram-positive and Gram-negative bacteria and are prospective for bio-imaging, as well as antimicrobial agents. Dr. Ilana Perelshtein is the Head of Synthesis of Smart Materials Unit obtained her M.Sc. degree (2005) in the field of Physical Chemistry and the Ph. D. (2009) in Chemistry of Materials at Bar-Ilan University. Ilana has developed a one-step process for synthesis of antibacterial nanoparticles and their subsequent coating on surfaces by the sonochemical technique, which was licensed and up-scaled. Additional expertise of Perelshtein is Electron Microscopy. Dr. Nataliia Dudchenko has PhD degree in biophysics and is a Leading Researcher of Synthesis of Smart Materials Unit. • One-pot scale-up synthesis of magnetite nanoparticles with silica coating for bioconjugation, targeted purification/separation of biological compounds. • Development and integration of a device for magnetic measurements, based on the Ponderomotive method for the express determination of magnetization of magnetic samples. • Winning and become partners of EU Project (HORIZON-CL4-2023-RESILIENCE-01-22) «Multidimensional Integrated Quantitative Approach to Assess Safety and Sustainability Nanomaterials in Real Case Life Cycle Scenarios Using NanoSpecific Impact Categories» (INTEGRANO), September 2023. • The Review “Magnetite-Based Biosensors and Molecular Logic Gates: From Magnetite Synthesis to Application” was published in “Biosensors” (https:// doi.org/10.3390/bios13030304).
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