64 Prof. Gerber Doron The Mina & Everard Goodman Faculty of Life Sciences Member of BINA Nano-Biomedicine Center Nano-Bioconvergence Center Research Areas • Virus host interactions • System biology • Microfluidics Abstract Microfluidics at the front of research. Doron Gerber’s lab specializes in microfluidics. We have developed various microfluidic devices and models for the investigation of diverse biological research fields. The projects running in our lab since 2021 include: 1) Microfluidics screen for Nano bodies - in cooperation with the University Medicine Göttingen – Germany and the NanoTag Biotechnologies GmbH. 2) Personalized therapy of various cancer treatments towards minimal residual disease evaluation. 3) Proteomics research. 4) Microfluidics bridges between FACS and Mass spectrometry. 5) Proteomics research of C. Elegans model through Its entire life cycle. The ‘lab on chip’ laboratory in the leadership of prof. Doron Gerber uses the microfluidic platform to promote science in diverse fieldes as well as to give a solution to some of the most important issue in many medical and scentific fields. Publications 2022 and 2023 • Bernard Moerdler, Matan Krasner, Elazar Orenbuch, Avi Grad, Benjamin Friedman, Eliezer Graber, Efrat Barbiro-Michaely, Doron Gerber. “PTOLEMI: Personalized Cancer Treatment through Machine Learning-Enabled Image Analysis of Microfluidic Assays”. Diagnostics, 2023. • Donald Penning, Simona Cazacu, Raphael Nizar, Cunli Xiang, Hodaya Goldstein, Matan Krasner, Efrat Barbiro-Michaely, Doron Gerber, Gila Kazimirsky, Lisa Rogers, Stephan Brown, Chaya Brodie. “Syst-24 Propofol ExErts Anti-Tumor Effects in Glioma amd thr Tumor Microenvironment Via Non-Coding RNAS and Secreted Exosomes”. NeuroOncology Advances, 2023. • Rephael Nizar, Simona Cazacu, Cunli Xiang, Matan Krasner, Efrat BarbiroMichaely, Doron Gerber, J onathan Schwartz, Iris Fried, Shira Yuval, Aharon Brodie, Gila Kazimirsky, Naama Amos, Ron Unger, Stephen Brown, Lisa Rogers, Donald H Penning, Chaya Brodie. “Propofol Inhibits Glioma Stem Cell Growth and Migration and Their Interaction with Microglia via BDNF-AS and Extracellular Vesicles”. Cells, 2023. • Lev Brio, Danit Wasserman,Efrat Michaely-Barbiro, Gal Barazany-Gal, Doron Gerber, Amit Tzur. “Affinity microfluidics enables high-throughput protein degradation analysis in cell-free extracts”. Communications biology, 2022. • Dana Peleg-Chen, Guy Shuvali, Lev Brio, Amit Ifrach, Ortal Iancu, Efrat BarbiroMichaely, Ayal Hendel, Doron Gerber. “Microfluidic tool for rapid functional characterization of CRISPR complexes”. New Biotechnology, 2022. Saravanan, Akanksha Gupta, John HT Luong, Aharon Gedanken. “Antimicrobial Activities of Conducting Polymers and Their Composites”. Macromol, 2022. • Moorthy Maruthapandi, Arumugam Saravanan, John HT Luong, Aharon Gedanken. “Polydopamine decorated carbon dots nanocomposite as an effective adsorbent for phenolic compounds”. Journal of Applied Polymer Science, 2022. • Sayan Ganguly, Poushali Das, Arka Saha, Malachi Noked, Aharon Gedanken, Shlomo Margel. “Mussel-Inspired Polynorepinephrine/MXene-Based Magnetic Nanohybrid for Electromagnetic Interference Shielding in X-Band and Strain-Sensing Performance”. Langmuir, 2022. • Shanmugasundaram Manoj, Hari Krishna Sadhanala, Ilana Perelshtein, Aharon Gedanken. “Rhenium Sulfide Incorporated in Molybdenum Sulfide Nanosheets for High-Performance Symmetric Supercapacitors with Enhanced Capacitance”. ACS Applied Materials & Interfaces, 2022. • Sudhakar Pagidi, Hari Krishna Sadhanala, Kusha Sharma, Aharon Gedanken. “OnePot Synthesis of Deep Blue Hydrophobic Carbon Dots with Room Temperature Phosphorescence, White Light Emission, and Explosive Sensor”. Advanced Electronic Materials, 2022. • Vijay Bhooshan Kumar, Diwakar Kashyap, Hanan Teller, Medhanie Gebremedhin Gebru, Aharon Gedanken, Alex Schechter. “Methyl formate and dimethyl ether electro-oxidation on PtPdSn catalyst supported on carbon nanotube decorated with carbon dots”. Materials Today Sustainability, 2022. • Vijay Bhooshan Kumar, Ze’ev Porat, Aharon Gedanken. “Synthesis of Doped/ Hybrid Carbon Dots and Their Biomedical Application”. Nanomaterials, 2022. • Hari Krishna Sadhanala, Akanksha Gupta, Aharon Gedanken. “Ultra-low palladium engineered nickel sulfide heterostructure supported on 3D nickel foam as a highly efficient and stable electrocatalyst for water oxidation”. Journal of Electroanalytical Chemistry, 2022. Dr. Girshevitz Olga Head of Characterization Unit: MIXA (Microscopy, Ion Beam, and X-ray Analysis) Member of BINA staff Publications 2022 and 2023 • P. Landau, T. Saffar, I. Orion, O. Girshevitz, E. Tiferet. “Helium bubble formation in additive manufactured L-PBF AlSi10Mg”. Journal of Nuclear Materials, 2023.
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