65 Dr. Golub Eyal Department of Chemistry Member of BINA Nano & Advanced Materials Center Nano-Bioconvergence Center Nano-Biomedicine Center Research Areas Protein-DNA interactions and proteinbased materials Abstract: The Golub lab aims to elucidate the mechanisms that govern various aspects of nanobiotechnology and harness them to generate the next-generation of biomaterials. On the one hand, we focus on elucidating the various mechanisms that govern non-canonical DNA-protein interactions at important biological crossroads from a biophysical perspective. Derived insights could serve in the future as a solid foundation for the development of highly selective and specific ligands, both for therapeutic purposes as well as for the development of sensitive biosensors. Additionally, methods for the preparation of novel protein-based nanobiomaterials and nanoreactors are being devised based on revolutionary protein building blocks. Such materials aim to harness the structural diversity and precision that can be found in proteins with the nanosized effects that stem from nanostructures. Our work focuses on designing proteins for protein-based materials and to explore protein-DNA interactions. Publications 2022 and 2023 • Albert Kakkis, Eyal Golub, Tae Su Choi, F Akif Tezcan. “Redox- and metal-directed structural diversification in designed metalloprotein assemblies“. Chem. Commun., 2022. • Lior Shani, Avital Fried, Yafit Fleger, Olga Girshevitz, Amos Sharoni and Yosef Yeshurun. “Effect of Focused Ion Beam irradiation on superconducting nanowires”. Journal of Superconductivity and Novel Magnetism, 2022. • R. Shockner, S. Syniakina, V. Richter, O. Girshevitz, I. Edry, M Pinka. ”Ion irradiation effect on B2 single phase AlFeCoNi alloy”. Materials Characterization, 2022. • Pola Shriber, Efrat Shawat Avraham, Bibhudatta Malik, Eti Teblum, Olga Girshevitz, Ilana Perelshtein, Michal Ejgenberg, Yossef Gofer, Yana Zubarev, Phillip Nagler, Gilbert Daniel Nessim. “Controlling the morphology while retaining the unique SnS stoichiometry of bulk tin sulfide produced by the rapid method of heating Sn foil in sulfur vapor by vapor phase reaction using twofurnace chemical vapor deposition system”. Chemical Papers, 2022. • O. Girshevitz, N. Cohen-Sinai, A. Zahavi, Y. Vardizer, D. Fixler. “Trace Elements in Tears: Comparison of Rural and Urban Populations Using Particle Induced X-ray Emission”. Journal of Personalized Medicine, 2022. • N.M. Yitzhak, O. Girshevitz, A. Haran, A. Butenko, M. Kaveh, I. Shlimak. “Evidence of structural changes in ion-irradiated graphene independent of the incident ions mass”. Applied Surface Science, 2022. • Omer Kaspi, Osnat Israelsohn-Azulay, Yigal Zidon, Hila Rosengarten, Matea Krmpotić � , Sabrina Gouasmia, Iva Bogdanović � Radović � , Pasi Jalkanen, Anna Liski, Kenichiro Mizohata, Jyrki Räisänen, Olga Girshevitz, Hanoch Senderowitz. “Inter-laboratory workflow for forensic applications: Classification of car glass fragments”. Forensic Science International, 2022. • Mirit Hen, Leroy Dokhanian, Etai Grunwald, Matan Slook, Moshe Katzman, Maayan Priel, Olga Girshevitz, and Avi Zadok. “Thin layers analysis using surface acoustic wave-photonic devices in silicon-on-insulator”. Optics Express, 2022. Dr. Goldzak Tamar Faculty of Engineering Member of BINA Nano & Advanced Materials Center Nano-Energy Center Nano-Quantum Center Research Areas Exploring light and matter interactions in materials through quantum electronic structure simulations Our lab strives to understand and predict how does atomic and electronic structure of materials and molecules effect their optoelectronic and mechanical properties. Understanding microscopic properties of materials, will help in controlling chemical reactions on surfaces and electron transport in nanomaterials, improve optoelectronic properties of devices, and predict novel quantum materials. In the lab we will simulate materials properties, electronic transfer mechanisms, and chemical reactions on the computer. We will develop state of the art electronic structure for predicting properties of materials, we will focus on nano-materials and 2D quantum materials. Charge densities of the excited electron/ hole for CdSe quantum dot capped with methylamine ligands, using TDDFT electronic structure simulation.
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