67 dimensions and extremely high sensitivity, allowing us to use them for sensing minute fields at the nanoscale. The current projects focus on combining these two unique sensors to overcome many of the limitations of each system. For example, read the NV center’s quantum state using a charge detector made of a carbon nanotube. A second example is using the NV center for probing the electron state on the carbon nanotube with quantum coherence. These projects will pave the way for a quantum imaging technique that probes the quantum nature of a system at the nanoscale. Proposed imaging system of orbital moment of a single electron. A carbon nanotube is suspended between two metallic contacts and above a few metallic gates. A small quantum dot is formed in the center of the carbon nanotube and is populated with a single electron. The electron will circulate clockwise or anticlockwise depending on the external magnetic field. A diamond tip with a single NV center is brought few tens of nanometers away from the quantum dot. Publications 2022 and 2023 • Qing Hua Wang, Amilcar Bedoya-Pinto, Mark Blei, Avalon H Dismukes, Assaf Hamo, Sarah Jenkins, Maciej Koperski, Yu Liu, Qi-Chao Sun, Evan J Telford, Hyun Ho Kim, Mathias Augustin, Uri Vool, JiaXin Yin, Lu Hua Li, Alexey Falin, Cory R Dean, Fèlix Casanova, Richard FL Evans, Mairbek Chshiev, Artem Mishchenko, Cedomir Petrovic, Rui He, Liuyan Zhao, Adam W Tsen, Brian D Gerardot, Mauro Brotons-Gisbert, Zurab Guguchia, Xavier Roy, Sefaattin Tongay, Ziwei Wang, M Zahid Hasan, Joerg Wrachtrup, Amir Yacoby, Albert Fert, Stuart Parkin, Kostya S Novoselov, Pengcheng Dai, Luis Balicas, Elton JG Santos. “The magnetic genome of two-dimensional van der waals materials”. ACS nano, 2022. Michaelis, Gil Goobes, Emiliano Fratini, Enrico Ravera. “Lysozyme is Sterically Trapped Within the Silica Cage in Bioinspired Silica–Lysozyme Composites: A Multi-Technique Understanding of Elusive Protein–Material Interactions”. Langmuir, 2022. • Khadiza Begam, Lilian Cohen, Gil Goobes, Barry D Dunietz. “Solvent Dependent Nuclear Magnetic Resonance Molecular Parameters Based on a Polarization Consistent Screened Range Separated Hybrid Density Functional Theory Framework”. Journal of Chemical Theory and Computation, 2022. • Noam Pinsk, Avital Wagner, Lilian Cohen, Christopher JH Smalley, Colan E Hughes, Gan Zhang, Mariela J Pavan, Nicola Casati, Anne Jantschke, Gil Goobes, Kenneth DM Harris, Benjamin A Palmer. “Biogenic guanine crystals are solid solutions of guanine and other purine metabolites”. Journal of the American Chemical Society, 2022. • Raju Nanda, Shani Hazan, Katrein Sauer, Victoria Aladin, Keren KeinanAdamsky, Björn Corzilius, Ron Shahar, Paul Zaslansky, Gil Goobes. “Molecular differences in collagen organization and in organic-inorganic interfacial structure of bones with and without osteocytes”. Acta Biomaterialia, 2022. Dr. Hamo Assaf Department of Physics Member of BINA Nano-Electro Magnetism & Spintronics Center Research Areas The Lab for Quantum Imaging Abstract The lab is focused on using quantum sensors for imaging various physical properties at the nanoscale. The two main sensors are a sensor for electric potentials based on carbon nanotubes and a sensor for magnetic fields based on Nitrogen Vacancies (NV) in diamonds. Those sensors have a unique combination of small Dr. Hendel Ayal The Mina & Everard Goodman Faculty of Life Sciences Member of BINA Nano-Biomedicine Center Research Areas • Biotechnology • Genetic therapy • Genetic engineering • Developing CRISPR technology as a method of gene therapy for genetic diseases Abstract Precise and efficient CRISPR genome editing as a curative therapy for genetic disorders We are in the midst of a revolution in genome editing and CRISPR-Cas9 technology was the spark. With unprecedented rapidity, this technology has provided a straightforward, robust, and specific method for genome editing. Our research focuses on developing genome editing as curative therapy for geneticdiseases and cancer. Our lab is particularly interested in applying genome editing for gene therapy of hematopoietic genetic disorders such as severe combined immunodeficiency (SCID). SCIDs are a set oflife threatening genetic diseases in which patients are born with mutations in single genes, and are unable to develop functional immune system. While allogeneic bone marrow transplantation can be curative for these disorders, there remain significant limitations to this approach. We believe that the ultimate cure for these diseases will be transplantation of gene-corrected autologous CD34+ hematopoietic stem and progenitor cells (HSPCs). To be able to apply this approach in the clinic, we must assure that the genome-editing technology is efficient and safe. Hence, our research focuses on developing an optimized CRISPR- genome editing for robust, locusspecific and non-toxic functional gene correction in HSPCs. Additional aspect of our research focuses on applying the CRISPR technologyto treat malignancies
RkJQdWJsaXNoZXIy NDU2MA==