82 of disease, targeted drug delivery with reduced side effects, and novel therapeutic approaches. Our vision is to have a major impact on the future of medicine. Our multidisciplinary research approach integrates researchers from the fields of engineering, chemistry, biology and medicine, and consolidates advances in nanomaterials with imaging, specific biomarkers and therapeutics. Molecular CT imaging of cancer using targeted gold nanoparticles. Publications 2022 and 2023 • Yoray Sharon, Menachem Motiei, Chen Tzror-Azankot, Tamar Sadan, Rachela Popovtzer, Eli Rosenbaum. “A ‘golden’alternative for prevention of cisplatin nephrotoxicity in bladder cancer”. Cancer Nanotechnolgy, 2023. • Omer Gal, Oshra Betzer, Liat RoussoNoori, Tamar Sadan, Menachem Motiei, Maxim Nikitin, Dinorah FriedmannMorvinski, Rachela Popovtzer, Aron Popovtzer. “Antibody Delivery into the Brain by Radiosensitizer Nanoparticles for Targeted Glioblastoma Therapy”. Journal of nanotheranostics, 2022. • Alexey A Lipengolts, Yulia A Finogenova, Vsevolod A Skribitsky, Kristina E Shpakova, Adi Anaki, Menachem Motiei, Alevtina S Semkina, Maxim A Abakumov, Anna V Smirnova, Elena Y Grigorieva, Rachela Popovtzer. “CT and MRI Imaging of Theranostic Bimodal Fe3O4@ Au NanoParticles in Tumor Bearing Mice”. International Journal of Molecular Sciences, 2022. • Chen Tzror-Azankot, Adi Anaki, Tamar Sadan, Menachem Motiei, Rachela Popovtzer. “Phosphate-Trapping Liposomes for Long-Term Management of Hyperphosphatemia”. Materials, 2022. • Hilla Pe’er-Nissan, Hadas Ahdoot-Levi, Oshra Betzer, Pnina Shirel Itzhak, Niva Shraga-Heled, Iris Gispan, Menachem Motiei, Arthur Doroshev, Yaakov Anker, Rachela Popovtzer, Racheli Ofir, Gal Yadid. “Placenta-Derived Mesenchymallike Adherent Stromal Cells as an Effective Cell Therapy for Cocaine Addiction in a Rat Model”. Pharmaceutics, 2022. • Oshra Betzer, Yue Gao, Astar Shamul, Menachem Motiei, Tamar Sadan, Ronen Dr. Perelshtein Ilana BINA Manager Head of Smart Materials Unit Publications 2022 and 2023 • Dudchenko, N; Pawar, S; Perelshtein, I; Fixler, D. “Magnetite-Based Biosensors and Molecular Logic Gates: From Magnetite Synthesis to Application”. Biosensors - Basel, 2023 • Salha, BA; Saravanan, A; Maruthapandi, M; Perelshtein, I; Gedanken, A. “PlantDerived Nitrogen-Doped Carbon Dots as an Effective Fertilizer for Enhanced Strawberry Growth and Yield”. ACS ES&T Engineering, 2023. • Konar, R; Rajeswaran, B; Paul, A; Teblum, E; Aviv, H; Perelshtein, I; Grinberg, I; Tischler, YR; Nessim, GD. “CVD-Assisted Synthesis of 2D Layered MoSe2 on Mo Foil and Low Frequency Raman Scattering of Its Exfoliated Few-Layer Nanosheets on CaF2 Substrates”. ACS Omega 2022. • Durairaj, A ; Maruthapandi, M ; Luong, JHT; Perelshtein, I; Gedanken, A. “Enhanced UV Protection, Heavy Metal Detection, and Antibacterial Properties of Biomass-Derived Carbon Dots Coated on Protective Fabrics”. ACS Applied Bio Materials, 2022. • Shriber, P ; Avraham, ES; Malik, B; Teblum, E ; Girshevitz, O; Perelshtein, I; Ejgenberg, M ; Gofer, Y; Zubarev, Y; Nagler, P; Nessim, GD .; “Controlling the morphology while retaining the unique SnS stoichiometry of bulk tin sulfide produced by the rapid method of heating Sn foil in sulfur vapor by vapor phase reaction using two-furnace chemical vapor deposition system”. Chemical Papers, 2022. • Twitto, A; Stern, C; Poplinger, M; Perelshtein, I; Saha, S; Jain, A; Koski, KJ; Deepak, FL; Ramasubramaniam, A; Naveh, D.; “Optoelectronics of Atomic Metal-Semiconductor Interfaces in TinIntercalated MoS2”. ACS Nano, 2022. • K. Dabbah, I. Perelshtein, A. Gedanken, Y. Houri-Haddad, O. Feuerstein. “Effects of ZnCuO nano-coated titanium surface on bacterial and host cells”. Materials, 2022. • P. Das, S. Ganguly, I. Perelshtein, S. Margel, and A.Gedanken “Acoustic Green Synthesis of Graphene-Gallium Nanoparticles and PEDOT:PSS Hybrid Coating for Textile To Mitigate Electromagnetic Radiation Pollution”. ACS Appl. Mater&Interf, 2022. • P. Shriber, M. Tkachev, A. Atkins, I. Perelshtein, S. Bretler, B. Schmerling, Y. Fleger*, G. Mariotto, M. Giarola, G. Daniel Nessim. “Synthesis of Nickel Sulfide Dendrites from Nickel Foil Using Thermal Annealing”. Materialia, 2022. • N. Dudchenko, S. Pawar, I. Perelshtein, D. Fixler. “Magnetite nanoparticles: synthesis and applications in optics and nanophotonics”. Materials, 2022. • I. Perelshtein, I. Levi, N. Perkas, A. Pollak, A. Gedanken. “CuO-coated Antibacterial and Antiviral Car Air-Conditioning Filters”. ACS. Appl. Mater.&Interf. 2022. • B. Malik, S. Majumder, R.Lorenzi, I. Perelshtein, M. Ejgenberg, A. Paleari, G. Daniel Nessim “Promising Electrocatalytic Water and Methanol Oxidation Reaction Activity by Nickel Doped HematiteSurface Oxidized Carbon Nanotubes Composite Structures”. ChemPlusChem, 2022. Prof. Popovtzer Rachela Faculty of Engineering Member of BINA Nano-Biomedicine Center Nano-Bioconvergence Center Research Areas • Molecular CT imaging of cancer using targeted gold nanoparticles • Theranostic approaches for Alzheimer’s and Parkinson’s Diseases • Metabolic based imaging and therapy. • Optical/chamical imaging of enzymatic activity • Nanoparticle-based strategies for targeted drug delivery • In-vivo cell tracking techniques Abstract Nanotheranostics for Personalized Medicine We strive to develop innovative nanotechnology-based solutions for broad applications, including early diagnosis
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