2023 ANNUAL REPORT | BAR-ILAN INSTITUTE

83 Prof. Rosenbluh Michael Department of Physics Member of BINA Nano-Photonics Center Nano-Quantum Center Research Areas • Laser spectroscopy • Propagation of short pulses in in homogeneously broadened media • Bulk and surface light scattering • Linear and non-linear optical properties • Heat and mass transfer during interaction of short laser pulses with optical nanocomposite materials Abstract We explore the interaction of light and matter in both the classical regime and in the quantum regime. Applications to sensing technology, secure communications and optical frequency standards are experimentally pursued in the lab. Closed cycle, 3.5 K, cryostat, with a built-in confocal microscope, for studying quantum emitters and superconducting single photon detectors. Yehuda,Ayelet Atkins, Cyrille J Cohen, Mingwu Shen, Xiangyang Shi, Rachela Popovtzer. “Multifunctional nanoprobe for real-time in vivo monitoring of T cell activation”. Nanomedicine: Nanotechnology, Biology and Medicine, 2022. • Victoria O Shipunova, Mariia M Belova, Polina A Kotelnikova, Olga N Shilova, Aziz B Mirkasymov, Natalia V Danilova, Elena N Komedchikova, Rachela Popovtzer, Sergey M Deyev, Maxim P Nikitin. “Photothermal Therapy with HER2Targeted Silver Nanoparticles Leading to Cancer Remission”. Pharmaceutics, 2022. Publications 2022 and 2023 • Ajoy Maji, Kinjal Dasbiswas, Yitzhak Rabin. “Shape Transitions in Network Model of Active Elastic Shells”. Soft Matter, 2023. • Harsh Vashistha, Joanna Jammal-Touma, Kulveer Singh, Yitzhak Rabin, Hanna Salman. “Bacterial cell-size changes resulting from altering the relative expression of Min proteins”. Nature Communications, 2023. • Ajoy Maji, Yitzhak Rabin. “Network model of active elastic shells swollen by hydrostatic pressure”. Soft Matter, 2022. Prof. Rabin Yitzhak Department of Physics Member of BINA Nano & Advanced Materials Center Research Areas • Biophysics • Soft condensed matter (polymers, gels, liquid crystals) and disordered solids • Interfaces and confined systems • Geometrical methods in physics Abstract Soft and Biological Matter Theoretical studies of APD (All Particles are Different) fluids and solids, Microbiomehost adaptation, Bacterial division, Reactions and phase separation in active systems, Scale-dependent viscoelasticity, NPC (nuclear pore complex) morphology. Publications 2022 and 2023 • Matan Slook, Saawan Kumar Bag, Moshe Katzman, Dvir Munk, Yuri Kaganovskii, Michael Rosenbluh, Naor Inbar, Inbar Shafir, Leroy Dokhanian, Maayan Priel, Mirit Hen, Elad Zehavi, Avi Zadok. “16-channel O-band silicon-photonic wavelength division multiplexer with a 1 nm channel spacing”. Optics Continuum, 2022. • Yu Kaganovskii, V Freilikher, M Rosenbluh. “Evolution of surface relief gratings in As20Se80 amorphous chalcogenide films under laser illumination”. Journal of NonCrystalline Solids, 2022. Prof. Ruthstein Sharon Department of Chemistry Member of BINA Nano & Advanced Materials Center Nano-Electro Magnetism & Spintronics Center Nano-Biomedicine Center Research Areas • plasmonics • molecules-surface plasmons interaction • molecular dynamics • strong coupling systems • Near field spectroscopy • Second Harmonic Generation (SHG) Abstract Biomolecular EPR Spectroscopy lab Our work focuses on the cellular copper cycle. The knowledge gained by studying the copper cycle in eukaryotic and prokaryotic systems is then used to develop new biomarkers and therapeutic agents that are dependent on the copper cycle. We believe that a basic understanding of the chemical and biological systems is essential for developing the next generation of biomarkers and drugs that will be adopted in the clinic. Our group utilizes various spectroscopic (specifically EPR spectroscopy) and computational methods to resolve cellular metal transfer mechanisms in vitro and in cells at the molecular level. Moreover, when a therapeutic or diagnostic compound is

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