88 structures of the gels, i.e. aligning the fibers as topographical cues, we optimize growth and direct regeneration. We combine magnetic nanoparticles (MNPs) within potentially-injectable collagen hydrogels and, by applying an external magnetic field we are able to control MNP structure and gel fiber orientation. Both MNPs and gel fibers serve as guiding cues and drug carriers. © Copyright Orit Shefi Lab, all Right Reserved Publications 2022 and 2023 • Yuxiang Zhu, Tina Kwok,Joel C Haug, Shenghan Guo, Xiangfan Chen, Weiheng Xu, Dharneedar Ravichandran, Yourka D Tchoukalova, Jeffrey L Cornella, Johnny Yi, Orit Shefi, Brent L Vernon, David G Lott, Jessica N Lancaster, Kenan Song. “3D Printable Hydrogel with Tunable Degradability and Mechanical Properties as a Tissue Scaffold for Pelvic Organ Prolapse Treatment”. Advanced Materials Technologies, 2023. • Eli Varon,Gaddi Blumrosen, Orit Shefi. “A predictive model for personalization of nanotechnology-based phototherapy in cancer treatment”. Frontiers in Oncology, 2023. • Dafna Rivka Levenberg, Eli Varon, Ganit Indech, Tal Ben Uliel, Lidor Geri, Amos Sharoni, Orit Shefi. “A streptavidin– biotin system combined with magnetic actuators for remote neuronal guidance”. Journal of Biological Engineering, 2023. • Elina Haimov-Talmoud, Michal Rosenberg, Sofia Arshavsky-Graham, Eli Varon, Orit Shefi, Ester Segal. “Biolistic Delivery of Photosensitizer-Loaded Porous Si Carriers for Localized Photodynamic Therapy”. Advanced Materials Technologies, 2023. • Ganit Indech, Lidor Geri, Chen Mordechai, Yarden Ben Moshe, Yitzhak Mastai, Orit Shefi, Amos Sharoni. “Controlled synthesis of multifunctional dome-shaped microand nano-structures via a robust physical route for biological applications”. Journal of Materials Chemistry B, 2023. • Eli Varon, Gaddi Blumrosen, Moshe Sinvani, Elina Haimov, Shlomi Polani, Michal Natan, Irit Shoval, Avi Jacob, Ayelet Atkins, David Zitoun, Orit Shefi. “An engineered nanocomplex with photodynamic and photothermal synergistic properties for cancer treatment”. International Journal of Molecular Sciences, 2022. • Ariel Halevi, Nairouz Farah, Nisan Ozana, Sharon Cohen, Assaf Shoval, Orit Shefi, Yossi Mandel, Zeev Zalevsky. “Remote photonic sensing of action potential in mammalian nerve cells via histogrambased analysis of temporal spatial Prof. Shlimak Issai Department of Physics Member of BINA Nano-Electro Magnetism & Spintronics Center Research Areas Experimental studies of transport phenomena and electronic properties of disordered solids: • doped semiconductors • impure metals • conducting polymers • hopping conductivity • magnetoresistance • metal-insulator transition • electron-electron interactions Abstract Raman scattering spectra in irradiated graphene The repeatability of the Raman scattering (RS) spectra was analyzed in monolayer and bilayer graphene films. Position and width of the RS lines together with their intensity were measured in samples where graphene film was supported by a substrate and where the film was suspended over pits in the substrate. Relatively large fluctuations were observed upon repeated measurements at the same point both in supported and suspended samples. In bilayer graphene samples, the repeatability is reduced due to additional fluctuations in the twist angle between two misoriented layers. The average position of the RS lines is shifted in opposite directions and makes it possible to distinguish between bilayer and monolayer films, despite the similarity in the RS spectra. acoustic vibrations”. Optics Express, 2022. • Reut Plen, Alejandra Smith, Ofir Blum, Or Aloni, Uri Locker, Zehavit Shapira, Shlomo Margel, Orit Shefi. “Bioengineering 3D Neural Networks Using Magnetic Manipulations”. Advanced Functional Materials, 2022. Prof. Shohat-Ophir Galit The Mina & Everard Goodman Faculty of Life Sciences Member of BINA Nano-Biomedicine Center Nano-Robotics Center Research Areas Neurogenetics of motivation and social behavior Abstract Motivation is the process that initiates, guides, and maintains goal-oriented behavior, which includes the biological forces that activate behavior. At our lab, we try to bridge the gap between behavioral phenomena and the cellular machinery that encodes information on gradual changes in drive level and decodes it into a graded behavior. Localization of RNA molecules at a nano scale resolution within Neuropeptide F neurons. In collaboration with the Alon lab. Publications 2022 and 2023 • NM Yitzhak, O Girshevitz, A Haran, A Butenko, M Kaveh, I Shlimak. “Evidence of structural changes in ion-irradiated graphene independent of the incident ions mass”. Applied Surface Science, 2022.
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